![SYNERGY & BUG: "Pandora's box" + trinket "butter" which allows for infinite drops. BUG is explained in the comments. : r/bindingofisaac SYNERGY & BUG: "Pandora's box" + trinket "butter" which allows for infinite drops. BUG is explained in the comments. : r/bindingofisaac](https://external-preview.redd.it/8Mue4Nph5vV9iwQ7tAAtEn9CvvogzskgLdSJ-SbyPJE.png?format=pjpg&auto=webp&s=88668c4ba1250f96e53aec0c28e4efff920e5a85)
SYNERGY & BUG: "Pandora's box" + trinket "butter" which allows for infinite drops. BUG is explained in the comments. : r/bindingofisaac
![🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: Pandora's box! this is one of a few "one use items" that destroy themselves when used. 1-5 are ok, but rolling a 6 on this 🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: Pandora's box! this is one of a few "one use items" that destroy themselves when used. 1-5 are ok, but rolling a 6 on this](https://pbs.twimg.com/media/DiVQxMYV4AA5wBD.png:large)
🜏 Edmund McMillen 🜏 on Twitter: "Spoiler: Pandora's box! this is one of a few "one use items" that destroy themselves when used. 1-5 are ok, but rolling a 6 on this
![Brimstone is possible in greed mode, but I've only ever found it through Pandora's box or sacrificial alter : r/bindingofisaac Brimstone is possible in greed mode, but I've only ever found it through Pandora's box or sacrificial alter : r/bindingofisaac](https://preview.redd.it/uxsjtej4a2q61.jpg?width=640&crop=smart&auto=webp&s=5cd723c4ba838fcba34fd86df326549c0540ddf6)
Brimstone is possible in greed mode, but I've only ever found it through Pandora's box or sacrificial alter : r/bindingofisaac
![The Void + Pandora's Box results is some incredibly powerful synergy, depending on the floor : r/bindingofisaac The Void + Pandora's Box results is some incredibly powerful synergy, depending on the floor : r/bindingofisaac](https://preview.redd.it/l4iykonv2m7y.jpg?auto=webp&s=bd6be0b72ab3e8c9221c2e2dbdc7fa877c082627)